Interim Clinical Operations Leader
Placing an Interim Clinical Operations Leader to coordinate global cross-functional teams and drive early-phase clinical trials for TargImmune’s non-viral vector immuno-oncology platform.

The Client
TargImmune is a clinical-stage biotechnology company developing targeted immunotherapies for the treatment of solid tumours. The company focuses on improving the delivery of immune-modulating agents directly to the tumour microenvironment through proprietary targeting technologies. By enhancing localisation and reducing systemic exposure, TargImmune aims to increase therapeutic efficacy while minimising side effects, advancing novel immune-oncology approaches for patients with high unmet medical need. TargImmune has a unique dsRNA non-viral vector delivery platform which, by mimicking a virus, harnesses the body's powerful antiviral defences to address cancer tumours including distant metastases.
The Situation
TargImmune required an Interim Clinical Operations Leader to provide senior operational leadership across its clinical development activities. The role demanded strong experience in early-phase clinical trials, particularly Phase 1–2 studies in immune-oncology solid tumours, as well as the ability to operate hands-on within a small biotech environment. The company needed immediate support to coordinate cross-functional teams across multiple geographies, manage study start-up and execution, and ensure timelines, quality and regulatory compliance were maintained. An interim solution was selected to deliver accountability, structure and operational continuity during a critical phase of clinical execution with limited internal resources.
The Outcome
We placed an Interim Clinical Operations Leader for fourteen months who assumed full accountability for the execution of the clinical operations strategy. The interim coordinated cross-functional teams, oversaw study start-up activities, site selection and monitoring plans, and maintained close control of timelines, budgets and resourcing. They provided leadership throughout project implementation, proactively identified operational risks, and supported contingency planning to safeguard delivery.
The interim also ensured compliance with ICH-GCP and regulatory requirements, participated in audits and inspections, and contributed to process improvements within the programme. Working in a highly hands-on manner, they integrated quickly with project leadership and external partners, stabilising clinical operations and supporting successful study progression through to defined project milestones.






