Placing an Interim Clinical Operations Leader to coordinate global cross-functional teams and drive early-phase clinical trials for TargImmune’s non-viral vector immuno-oncology platform.

Client logo for The RSA Group Interim Clinical Operations Leader case study representing life sciences leadership search outcomes.

The Client

TargImmune is a clinical-stage biotechnology company developing targeted immunotherapies for the treatment of solid tumours. The company focuses on improving the delivery of immune-modulating agents directly to the tumour microenvironment through proprietary targeting technologies. By enhancing localisation and reducing systemic exposure, TargImmune aims to increase therapeutic efficacy while minimising side effects, advancing novel immune-oncology approaches for patients with high unmet medical need. TargImmune has a unique dsRNA non-viral vector delivery platform which, by mimicking a virus, harnesses the body's powerful antiviral defences to address cancer tumours including distant metastases.

The Situation

TargImmune required an Interim Clinical Operations Leader to provide senior operational leadership across its clinical development activities. The role demanded strong experience in early-phase clinical trials, particularly Phase 1–2 studies in immune-oncology solid tumours, as well as the ability to operate hands-on within a small biotech environment. The company needed immediate support to coordinate cross-functional teams across multiple geographies, manage study start-up and execution, and ensure timelines, quality and regulatory compliance were maintained. An interim solution was selected to deliver accountability, structure and operational continuity during a critical phase of clinical execution with limited internal resources.

The Outcome

We placed an Interim Clinical Operations Leader for fourteen months who assumed full accountability for the execution of the clinical operations strategy. The interim coordinated cross-functional teams, oversaw study start-up activities, site selection and monitoring plans, and maintained close control of timelines, budgets and resourcing. They provided leadership throughout project implementation, proactively identified operational risks, and supported contingency planning to safeguard delivery.

The interim also ensured compliance with ICH-GCP and regulatory requirements, participated in audits and inspections, and contributed to process improvements within the programme. Working in a highly hands-on manner, they integrated quickly with project leadership and external partners, stabilising clinical operations and supporting successful study progression through to defined project milestones.

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100%

Executive Retention ~12mo

5,600

Succesful Appointments

94%

Client Satisfacion Rate

6,800+

Subscribed Leaders & Executives

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United Kingdom

RSA Consulting Ltd & RSA Interims Ltd

The Gate House, Fretherne Road

Welwyn Garden City

Hertfordshire, AL8 6NS

+44 (0) 203 818 8820

hq@thersagroup.com


RSA Consulting Ltd (Company No: 01803896) and RSA Interims Ltd (Company No: 08433229), both registered in England and Wales.

Germany

RSA Consulting GmbH

Theodor-Heuss-Allee 112

60486 Frankfurt

+49 69 667741-470

hq@thersagroup.com


Represented by Nicholas D. Stephens, Kristian Juergensen


Registered in the Commercial Register (Handelsregister), Registration Court: District Court (Amtsgericht) Frankfurt am Main, Register Number: HRB 73074


German VAT Registration Number: VAT registration number according to § 27a of the German Value Added Tax Act (Umsatzsteuergesetz): DE 814 029 343

Switzerland

RSA AG

Hochbergerstrasse 70

4057 Basel

+41 61 563 0188

hq@thersagroup.com


Represented by Nicholas D. Stephens, Kristian Juergensen, Peter Dahinden


Swiss Register Entry & UID: Registered in the Commercial Register (Handelsregister), UID / Enterprise Identification Number: CHE-109.711.591

Singapore

The RSA Group Pte.Ltd

808 French Road

Kitchener Complex 

#07-163

Singapore 200808

+65 6 294 4588,

hq@thersagroup.com


Company EA Number: 07S5575.

Nicholas D. Stephens EA Registration Number: R1107308.

The RSA Group operates through RSA (Holdings) Ltd and its subsidiaries; RSA Consulting Ltd , RSA Interims Ltd , both registered in England and Wales and RSA Consulting GmbH, RSA AG and The RSA Group Pte.Ltd. Registered Office for RSA Holding is: The Gate House, Fretherne Road, Welwyn Garden City, Hertfordshire, AL8 6NS. The RSA Group is a premier global executive search, interim / fractional leadership and advisory firm specialising exclusively in the Life Sciences sector, dedicated to uniting leadership with innovation-driven organisations to accelerate the discovery and delivery of therapies. Registered with the Information Commissioner’s Office (ICO) in full compliance with the Data Protection Act 2018 and UK GDPR.